Anti-pasteurellosis serum
Anti-Pasteurellosis Serum
For Cattle, Sheep, and Swine
Pharmacotherapeutic Group
Immunobiological veterinary preparation (hyperimmune serum)
Target Species
Cattle, sheep, swine
Description
The product is a preserved blood serum obtained from producer animals after hyperimmunization with inactivated antigen strains of Pasteurella multocida (14, 24, 655, 796, 877, 5264).
The serum is an opalescent liquid ranging in color from transparent red to dark brown.
During storage, the formation of a fat-like film and a slight grayish-white sediment is permissible; both disappear after shaking.
Packaging
The serum is packaged in sterile glass vials:
-
100 ml
The vials are hermetically sealed with rubber stoppers and covered with aluminum caps.
Storage Conditions
Store in the manufacturer’s original packaging, protected from light, at temperatures between 2°C and 15°C.
Shelf Life
4 years from the manufacturing date when transportation and storage conditions are respected.
After opening the vial, the remaining serum must not be stored.
Do not use after the expiration date.
Biological Properties
The serum contains specific antibodies against the causative agent of pasteurellosis.
The product is safe and non-reactogenic and possesses both therapeutic and prophylactic properties.
Passive immunity develops immediately after administration and lasts for up to 7 days.
Indications for Use
The anti-pasteurellosis serum is used for the treatment and prevention of pasteurellosis in cattle, sheep, and swine on farms considered unfavorable for pasteurellosis.
Directions for Use and Dosage
Administration of the product must be carried out in accordance with aseptic and antiseptic rules.
Before administration:
-
Instruments must be sterilized by boiling;
-
A separate needle must be used for each animal;
-
The injection site should be shaved and treated with approved antiseptic agents.
The vial should be shaken before and during use.
Before administration, chilled serum should be warmed in a water bath to 36–37°C.
The serum must be used on the same day the vial is opened.
Unused serum does not require special disposal and poses no danger to humans, animals, or the environment.
Dosage
The serum is administered subcutaneously in the following doses:
|
Animal |
Dose |
|---|---|
|
Calves, lambs, piglets |
10–30 ml |
|
Cattle, sheep, swine |
30–40 ml |
Note
Therapeutic use of the serum is most effective during the initial stage of the disease, at the first appearance of clinical symptoms.
In such cases, the serum is administered intramuscularly or intravenously at a double dose.
Special Precautions
Use of the serum in piglets and swine should first be tested on a small group of animals (3–5 heads) while monitoring their general condition.
If signs of anaphylaxis or allergic reactions occur, symptomatic (anti-allergic) treatment should be administered.
In such cases, it is recommended to dilute the serum dose in isotonic sodium chloride solution at a ratio of 1:4.
Along with serum administration, special attention should be paid to veterinary-sanitary and zoohygienic measures aimed at eliminating infection and increasing the resistance of the animals’ организма.
Withdrawal Period
After administration of the serum:
-
Slaughter of animals for meat;
-
Use of milk for food purposes;
is permitted without restriction.
Personal Safety Measures
When handling the serum, general personal hygiene and safety rules established for the use of veterinary medicinal products must be observed.